N-Glycolylneuraminic acid
| CAS No.: 1113-83-3 | Request for quotation |  |
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N-Glycolylneuraminic acid (Neu5Gc) is an abundant sialic acid, occurring in the glycoconjugates of most deuterostome animals. Neu5Gc differs from Neu5Ac by an additional oxygen atom in the N-acyl moiety. It is generally accepted that normal human tissues do not contain Neu5Gc. Interestingly, chickens also appear to lack Neu5Gc. In cancer tissues,Neu5Gc is differentially expressed on gangliosides or glycoproteins. |
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N-Glycolylneuraminic acid Specification
| Appearance | White to off-white powder | Standard Packing | 10g/bag or per customer request | |
| Assay (HPLC) | ≥ 95% | Inventory | Normally we have N-Glycolylneuraminic acid in stock | |
| Loss on drying | ≤ 2.0% | |||
| Lead | ≤ 10 ppm | N-Glycolylneuraminic Acid physical parameters | ||
| Residue on Ignition | ≤ 1.0% | CAS No: | 1113-83-3 | |
| Melting Point | 184 --186 ° C | Formula | C11H19NO10 | |
| Molecular Weight | 325.57 | |||
| Synonym | Neu5Glc, NeuNGl, Neu5Gc | |||
| Structure |  |
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| Certificate of Analysis | N-Glycolylneuraminic acid COA | |||
| Literature | N-Glycolylneuraminic acid literature | |||
| MSDS | N-Glycolylneuraminic acid MSDS | |||
| References: | ||||
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1. |
Nystedt, Anderson, Hirvonen et al.: STEM CELLS 2010; 28: 258-267. Human CMP-N-Acetylneuraminic Acid Hydroxylase Is a Novel Stem Cell Marker Linked to Stem Cell-Specific Mechanisms. Full text | |||
| 2. | Oliver M. T. Pearce, Ajit Varki et al.: Carbohydrate Research 345 (2010) 1225–1229. Chemo-enzymatic synthesis of the carbohydrate antigen N-glycolylneuraminic acid from glucose | |||
| 3. | Igor O. Nasonkin et al.: Experimental Neurology 201 (2006) 525–529. Nonhuman sialic acid Neu5Gc is very low in human embryonic stem cell-derived neural precursors differentiated with B27/N2 and noggin: Implications for transplantation | |||
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N-Glycolylneuraminic acid
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