Naringenin
| CAS No.: 67604-48-2 | Request for quotation |  |
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Naringenin is a flavanone, a type of flavonoid, that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. It is the predominant flavanone in grapefruit. Naringenin has various effects such as anti-atherogenic, anti-oxidant, and anti-inflammatory effects. Naringenin is effective at concentrations that are an order of magnitude below the toxic threshold in primary human hepatocytes and in mice. [3] Naringenin belongs to the class of flavonoids called the flavanones. Naringenin is almost insoluble in water and is soluble in organic solvents such as alcohol.Naringenin is derived from the hydrolysis of glycone forms of this flavanone, such as naringin or narirutin. |
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Naringenin Specification
| Appearance | Light-Yellow Powder | Standard Packing | 500g/bag or per customer request | |
| Loss on drying | ≤ 5% | Inventory | Normally we have Naringenin in stock | |
| Residue on ignition | ≤ 5 % | |||
| Heavy metals | ≤ 10 ppm | Naringenin physical parameters | ||
| Residual Solvent | ≤ 0.05% | CAS No: | 67604-48-2 | |
| Pb | ≤ 2 ppm | Formula | C15H12O5 | |
| Assay | ≥ 98% | Molecular Weight | 272.25 | |
| Total of bacteria | ≤ 1000 cfu/g | Synonym | (±)-Naringenin, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4',5,7-Trihydroxyflavanone; 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one | |
| Fungi | ≤ 100 cfu/g | Structure |  |
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| E.coli | Negative | |||
| Salmosella | Negative | |||
| Certificate of Analysis | Naringenin COA | |||
| Literature | Naringenin literature | |||
| MSDS | Naringenin MSDS | |||
| References: | ||||
| 1. | Abdolkarim Mahrooz et. a.: Clinical Biochemistry 44(13), Supplement, September 2011, Pages S249. Naringenin is an inhibitor of human serum paraoxonase. DOI: 10.1016/j.clinbiochem.2011.08.617 | |||
| 2. | Naringenin suppresses the production of thymic stromal lymphopoietin through the blockade of RIP2 and caspase-1 signal cascade in mast cells. DOI: 10.1016/j.ejphar.2011.09.163 | |||
| 3 | Naringenin has also been shown to reduce hepatitis C virus production by infected hepatocytes (liver cells) in cell culture. This seems to be secondary to Naringenin's ability to inhibit the secretion of very-low-density lipoprotein by the cells. | |||
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