|CAS No.: 104987-11-3||Our Tacrolimus is GMP certificate and USP grade||Request for quotation|
|Dihydroxy-Tacrolimus is also available, click here|
Tacrolimus, an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Tacrolimus (FK506) Specification (USP)
|Appearance||White crystalline powder||Standard Packing||100g/bag or per customer request|
|Purity (HPLC)||98%-102%||Inventory||Normally we have Tacrolimus (FK506), GMP certificate, USDMF in stock|
|Residue on Ignition||< 0.1%|
|Heavy metal||< 10 ppm||Tacrolimus (FK506) physical parameters|
|Optical rotation||-110° ~ -115°||CAS No:||104987-11-3|
|Water||< 4%||Formula||C44H69NO12 · H2O|
|Total impurity||< 1.0 %||Molecular Weight||822.03|
|Ascomycin||< 0.5%||Synonym||Advagraf; FR 900506; Fujimycin; L 679934; Prograf; Protopic; TacroBell; Tacrolimus; Tsukubaenolide|
|Total other impurity||< 0.5%||Structure|
Why is tacrolimus prescribed?
Tacrolimus is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How should this medicine be used?
Continue to take tacrolimus even if you feel well. Do not stop taking tacrolimus without talking to your doctor. You will probably take tacrolimus for a long time.
What special precautions should I follow?
·Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially amiloride (Midamor, Moduretic), bromocriptine (Parlodel), carbamazepine (Tegretol), cimetidine (Tagamet), cisapride (Propulsid), clarithromycin (Biaxin), clotrimazole (Mycelex, Lotrimin), cyclosporine (Neoral, Sandimmune), danazol (Danocrine), diltiazem (Cardizem), erythromycin (E-Mycin), fluconazole (Diflucan), ganciclovir (Cytovene), HIV protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir), itraconazole (Sporanox), ketoconazole (Nizoral), methylprednisolone (Medrol), metoclopramide (Reglan), nefazodone (Serzone), nicardipine (Cardene), nifedipine (Adalat, Procardia), omeprazole (Prilosec), oral contraceptives (birth control pills), phenobarbital, phenytoin (Dilantin), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane), spironolactone (Aldactone), triamterene-containing drugs (Dyazide, Dyrenium, Maxzide), troleandomycin (Tao), verapamil (Calan, Isoptin), and vitamins. Do not take antacids within 2 hours of taking tacrolimus.
What special dietary instructions should I follow?
What should I do if I forget a dose?
What side effects can tacrolimus cause?
If you experience any of the following symptoms, call your doctor immediately:
What storage conditions are needed for tacrolimus?
In case of emergency/overdose
What other information should I know?
Tacrolimus can raise your blood pressure. Talk to your doctor about checking your blood pressure regularly.
Before receiving any vaccinations, tell your doctor that you are taking tacrolimus.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
|Certificate of Analysis||Tacrolimus (FK506) COA|
|Literature||Tacrolimus (FK506) literature|
|MSDS||Tacrolimus (FK506) MSDS|
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